The American FDA. USA approves a specific prescription product for the treatment of attacks caused by Dravet syndrome, Lennox-Gastaut syndrome or the tubular sclerosis complex. It is unclear whether other forms of CBD are useful for seizure. Taylor L, Gidal B, Blakey G, Tayo B, Morrison G. A Stage I, randomized, double-blind, placebo-controlled, single-use, multiple dose and determination of the safety, tolerability and pharmacokinetic effects of highly purified cannabidiol in healthy subjects.
Doses ranged from 20 to 250 mg / day with a duration of treatment from 8 to 13 weeks. Isolated or exact vegetable compounds rich in CBD were administered in the form of hard oral capsules or oil. One study was considered to have an uncertain risk of bias and two at high risk. Possible health benefits include reducing inflammation and pain.
Cannabis plants grown with a high THC content are generally called marijuana. That oil can be taken when a liquid, capsule, gummy or inhaled through the vapeo. It can also be added as an ingredient in products such as lotions and skin patches. Research cbd products suggests that CBD may undermine the effectiveness of some medications and increase the risks of others, especially at high doses. “Highly concentrated CBD dyes can interfere with the liver enzyme system that metabolizes many drugs,” says Abrams.
Other research shows that CBD can also help with other health problems, including multiple sclerosis, pain and anxiety. Beyond that, It is generally assumed that CBD is not a habit-former, and does not produce the same high of marijuana with THC. Further away, Animal studies have shown that CBD may have anti-inflammatory effects that can treat chronic pain or inflammatory diseases in animals, and others, Limited research indicates that CBD can help treat mental disorders. In all studies, expect one that uses plant extracts to receive purified CBD. Data from preclinical animal models indicate that purified CBD may have a bell-shaped response that was also confirmed in two studies included in this assessment .
“Patients are generally reluctant to tell their oncologists about complementary therapies in general for fear of being punished,” said Abrams. However, if you have started using CBD, you should inform your doctor. For example, in New Jersey – which has recently expanded the categories of debilitating conditions eligible for state medical marijuana programs – State Health Commissioner Sheref Elnahal, M.D .
Most studies reported results differently and even if the same result was reported, it was measured differently. Assessment of the level of results was only performed for anxiety in social anxiety disorder and psychotic symptoms and cognitive function in patients with schizophrenia, according to the recommendations that apply the GRADE approach in narrative synthesis . Two studies evaluated anxiety in untreated SAD populations and three evaluated cognitive function and positive and negative symptoms in patients with schizophrenia. Although CBD is an essential part of medical marijuana, it is directly derived from the hemp plant, which is a premium for the marijuana plant. For example, some human clinical studies suggest that CBD may be effective in treating anxiety complaints, especially social anxiety, Bonn-Miller said.
Patients enrolled in the studies had higher infection, sleep problems and loss of appetite. Regarding safety concerns, most studies did not report AD with acute administration and mild to moderate adverse reactions with chronic administration. A better side effect profile was presented compared to other medicines . Chronic CBD administration for most of the included studies took several weeks (4 to 6 weeks).